Ointment Manufacturing Plant

The Ointment & Cream manufacturing plants for pharmaceutical & cosmetic industries for Manufacturing of Ointment, Cosmetic Cream, Lotion, Toothpaste emulsion & homogenizations. The Ointment & Cream Manufacturing Plants is a universal mixing system, World class Latest version technology with developed for the productions of emulsion and suspension in the pharmaceuticals & Cosmetic, FMCG industry in particular Western Europe; Eastern Europe; Middle East; Asia; Australia; North America; Africa; Central/South America, our systems are fully Automatic and delivering of best performances with reduced life-cycles costing. cleaning for every change over, UN-touched product transfer maintaining highest level of operational hygiene, etc.

We are your qualified system partner.

Semi solid manufacturing Plants are ideal tools for the pharmaceutical & cosmetic industries for the production of Ointment, Cream, Lotion, Gel, Toothpaste & emulsions & homogenization.

Fully automatic Ointment, Cream, Tooth Paste, Gel manufacturing plant consisting of

– Predetermined water phase vessel.
– Predetermined oil, wax, petroleum jelly phase vessel.
– Vacuum Homogenizer Mixer vessel.
– Vacuum Pump
– Storage vessel
– Interconnecting pipeline.
– Transfer Pumps (Bump Pump, Lobe Pump & Metering pumps)
– Integrated automatic control panel.
– Working Platform

GERMAN ENGINEERING – EXPERIENCE AND EXPERTISE

APPLICATIONS: Pharmaceuticals Ointment manufacturing plant – Sterile & Non-Steriles Ointment, Creams, Gel, Lotions, Medicated toothpaste etc many more.

 

Cosmetic Manufacturing plant – Lotion, Creams, Shaving Cream, Sun Cream, Gels, Hair Dyes, Creams Shampoo, Conditioner, Toothpaste, Bath Additive, Foot care Product and Many more.

Key features of Ointment Manufacturing Plant / Cream Manufacturing Plant.

• Processing system fully Automated
• Process parameters Flexible Setting
• Variables Speeds adjustment
• Semi – Contra Rotary Mixer – Agitators open slots scraper designs
• Loop Systems product re-circulations for smaller Lab batch sizes
• Ointment and Cream Pre-mix vessels for wax and water phase shall be Separate
• Heating / cooling and insulated jackets with temperature control and safety equipment
• Process piping with transfer Pump, Panel designs for automation plant
• In-line high shear mixer option
• Load cell for accurate weighing systems for Manufacturing Plant
• Cleaning-in-place cycles with Ointment and Cream dosing systems

VESSEL DESIGNS

• Vessels structure according to ASME rule and customized plan according to client’s necessities.
• Best mix of vessel and tumult framework, offering high profitability, quality and yield
• Conical plan and geometric proportions guarantee ideal item stream
• All surfaces calculated to guarantee simplicity of cleaning during CIP activities Easy to use INTERFACE

Processing and Manufacturing Equipment – more than 25 years of design and manufacturing experience, strong factory customization, quality assurance.

 

USER FRIENDLY INTERFACE

 

• The simple to-utilize blender control bundle can fuse process parameters stockpiling for straightforward and quick set-up
• PLC based, with contact screen MMI and SCADA bundles
• Choice of bundles to suit application prerequisites
• Flexible setup
• Manufacturing Vessel or Jacketed planetary blender
• Was stage vessel
• Water stage vessel
• Storage vessel
• Vacuum Systems
• Control Panel
• Product feeding.
• Working Plate form with stage
• Material move siphon to ship stuff from assembling vessel or meandering blender to capacity vessel and capacity vessel to Ointment (Tube) filling line.

CAPACITY : 5 – 10,000 Kgs.

Product highlights

	Consistency	Ideal uses
Lotion	thin, non-greasy	rapid absorption without residue
Cream	holds shape, viscous, non-greasy to mildly greasy	dry skin, rashes, or skin lesions that need protection against moisture loss
Ointment	thick, viscous, greasy	topical medications that need maximum product absorption
Gel	thick, non-greasy	extremely oily skin
Balm	very thick, waxy	dry skin in need of hydrating barrier and slow absorption

Ointments are viscous, unctuous, semisolid preparations containing either dissolved or suspended functional ingredients.

 

Agent Name	Discussion
Bacitracin	Only ointment formulations (500 units/g) of bacitracin, an antibiotic, are used for the treatment of eye infections. It is commonly employed for prophylaxis after eyelid surgery, eyelid lacerations, or on open periocular herpetic lesions to prevent secondary bacterial infection. Bacitracin is useful for periocular skin infections and may be used for bacterial conjunctivitis. It is a well-tolerated.
Chloramphenicol	The antibiotic chloramphenicol is used as a solution, 0.16-0.5%, or ointment, 1%. It is not widely prescribed in the United States because of concern about aplastic anemia developing, even with topical administration. It is active against many gram-positive and gram-negative bacteria, but it does not adequately cover Pseudomonas aeruginosa or Serratia marcescens.
Ciprofloxacin hydrochloride	the antibiotic ciprofloxacin, as a 0.3% solution or ointment, is used for the treatment of eye infections. It was the first topical fluoroquinolone approved for the treatment of both bacterial conjunctivitis and corneal ulcers. It is bactericidal with a very broad spectrum of coverage and minimal toxicity, and it is efficacious as monotherapy for bacterial keratitis. Ciprofloxacin can cause a white corneal precipitate with frequent application. These precipitates resolve upon discontinuation of the drops and cause no permanent damage or dysfunction.
Erythromycin	The antibiotic erythromycin is used as an ointment (0.5%) for prophylaxis after eyelid surgery, lid lacerations, or on open periocular herpetic lesions to prevent secondary bacterial infection. It is useful for staphylococcal blepharitis and in pediatric conjunctivitis.
Gentamicin sulfate, prednisolone acetate/gentamicin	the antibiotic gentamicin sulfate (solution, 0.3%; ointment, 0.3%) alone and a prednisolone acetate/gentamicin (solution, 1%/0.3%; ointment, 0.6%/0.3%) combination are used to treat eye infections. These agents provide better coverage of gram-negative than of gram-positive organisms, although topical gentamicin is effective against many of the common gram-positive organisms in external eye infections. They may be more likely to produce a toxic keratoconjunctivitis compared with other agents, which should be considered when signs and symptoms worsen after an initial improvement. Concentrated solutions (8-15 mg/ml) can be prepared for topical treatment of severe corneal ulcers. These drops are usually used in combination with a concentrated solution of cefazolin (50 mg/ml). A formulation combined with corticosteroid is available for use when anti-inflammatory treatment is necessary and steroids are not contraindicated. Corticosteroid-antibiotic combinations should never be used if there is a possibility of herpetic, fungal, or mycobacterial infection.
Levofloxacin	This topical fluoroquinolone antibiotic is used as a 0.5% solution. It has a very wide spectrum of coverage and good ocular penetration. It is frequently used perioperatively for prophylaxis after intraocular or corneal procedures.
Norfloxacin	The antibiotic norfloxacin is used as a topical 0.3% solution. This fluoroquinolone is not widely used because other topical formulations of this drug class are generally thought to provide better coverage and be better tolerated.
Ofloxacin	The antibiotic ofloxacin is used topically as a 0.3% solution. It has a spectrum of activity similar to ciprofloxacin. It is frequently used perioperatively for prophylaxis after intraocular and corneal procedures and has a label indication for treatment of corneal ulcers. There is some debate about which fluoroquinolone provides the most effective prophylaxis of eye infections.
Sulfacetamide sodium, prednisolone acetate/sulfacetamide, prednisolone phosphate/sulfacetamide, fluorometholone/sulfacetamide	Sulfacetamide sodium (solution or ointment, 10%), prednisolone acetate/sulfacetamide (suspension or ointment, 0.2-0.5%/10%), prednisolone phosphate/sulfacetamide (solution, 0.25%/10%), and fluoroethylene/sulfacetamide (suspension, 0.1%/10%) are all antibiotic preparations used for the treatment of eye infections. These agents are not usually prescribed as first line therapy because of gaps in coverage for Pseudomonas, Serratia, and many resistant staphylococcal strains, and because of a relatively high prevalence of allergies to sulfonamides. They are Indicated for adjunctive topical treatment for trachoma. Corticosteroid/sulfacetamide combinations are sometimes used for blepharitis treatment. Formulations containing corticosteroids are available for use when anti-inflammatory treatment is necessary, and corticosteroids are not contraindicated. Corticosteroid-antibiotic combinations should never be used if there is a possibility of active herpetic, fungal, or mycobacterial infection.
Tobramycin sulphate, dexamethasone/tobramycin	Tobramycin sulphate (solution or ointment, 0.3%), dexamethasone/tobramycin (suspension or ointment, 0.1% / 0.3%), is widely used for treatment of conjunctivitis. This antibacterial has a broad spectrum of coverage and low prevalence of allergy. The combination of tobramycin with a corticosteroid is used for postoperative prophylaxis and for the control of inflammatory conditions at risk for bacterial infection. A concentrated solution (8-15 mg/ml) is often prepared for treating corneal ulcers in combination with a concentrated solution of cefazolin (50 mg/ml). Corticosteroid-antibiotic combinations should never be used if there is a possibility of active herpetic, fungal, or mycobacterial infection.
Polymyxin B/bacitracin zinc	This combination of antibacterials is used as an ointment, 10,000-5,000 units/g. Polymyxin B provides gram-negative and bacitracin gram-positive coverage. Although it is not typically employed as first line treatment for conjunctivitis, it is often used for prophylaxis on eyelid lesions.
Polymyxin B/neomycin/bacitracin	This drug combination, which is used as an ointment (10,000 units-3.5 mg-5,000 units/g), has a broad spectrum of coverage because of its triple antibiotic combination. It is not typically employed as first line treatment for conjunctivitis because of a higher prevalence of allergies to neomycin compared with other available antibiotics.
Polymyxin B/neomycin/gramicidin	This combination, which is administered as a solution (10,000 units-1.75 mg-0.025 mg/ml), is similar to the triple antibiotic combination but contains gramicidin. It is not generally prescribed because of a higher incidence of allergies to neomycin as compared with other antibiotics.
Polymyxin B/trimethoprim	This broad-spectrum antibiotic solution has a lower incidence of allergy than do preparations containing neomycin or sulfacetamide.
Polymyxin B/neomycin/corticosteroid (dexamethasone, hydrocortisone, or prednisolone acetate)	These combinations are used for the treatment of inflammatory eye conditions with risk of infection. Steroid-antibiotic combinations should never be used if there is a possibility of herpetic, fungal, or mycobacterial infection.
Vancomycin	No commercially available topical vancomycin preparation is available, but it is sometimes prepared for topical treatment (20 mg/ml) of corneal ulcers or intravitreal injections (1 mg) for endophthalmitis in cases caused by gram-positive organisms that are resistant to other antibiotics. It is used in combination with amikacin (0.4 mg) or ceftriaxone (2 mg) for empirical intravitreal treatment of endophthalmitis.
Gatifloxacin	This antibacterial is one of three commercially available topical fluoroquinolones. It is effective in the treatment of some Mycobacterium species Mather et al (2002).
Moxifloxacin	Moxifloxacin is one of three commercially available fluoroquinolones that is effective in treating some Mycobacterium species. It is available as a preservative-free solution (0.5%) Kowalski et al (2003).
Amphotericin B	Amphotericin B is an antifungal that may be used for topical treatment (0.15% solution) of fungal keratitis, especially when it results from Candida spp. infection.
Natamycin	Natamycin is the only commercially available, topical antifungal (5% solution). It is especially useful for treating infections caused by Fusarium or Aspergillus.
Clotrimazole	Clotrimazole is an antifungal that may be prepared for topical treatment (0.1% to 1% solution), especially for Aspergillus keratitis. Miconazole, ketoconazole, fluconazole, and flucytosine have also been used orally or topically for persistent fungal infections.
Trifluorothymidine	Trifluorothymidine is a topical antiviral solution effective only for herpes simplex keratitis. It is ineffective for herpes zoster or other viral infections, and it may have toxic effect on the corneal epithelium.
Vidarabine	Vidarabine is a topical antiviral ointment (3%) used to treat HSV keratitis. Although it is considered less effective than trifluorothymidine, it may also cause less corneal toxicity.
Acycolovir, famciclovir and other antiviral agents	The antiviral agents acycolovir, famciclovir, and valacyclovir all are used orally for the treatment of herpes zoster ophthalmicus. They have been used as alternative drugs for HSV when topical therapy is not tolerated. They also provide prophylaxis against recurrent HSV disease. HEDS Group (1998). Ganciclovir and foscarnet are used for the treatment of cytomegalovirus retinitis. Extended-release intravitreal implants of ganciclovir are also available.
Povidone-iodine	Topical povidone-iodine solution (5%) is used as a preoperative disinfectant for the eyelid margin and conjunctiva. It is used for prophylaxis prior to intraocular surgery, where a 5% solution is applied to the ocular surface and rinsed off with sterile balanced saline solution Ciulla et al (2002).
Cefazolin	Cefazolin is not commercially available in a topical formulation, but it is often prepared as a concentrated solution (50 mg/ml) for the treatment of corneal ulcers. It is especially active against gram-positive organisms and is most commonly used in combination with an antibiotic with better gram-negative coverage such as tobramycin.

 

We supply and export in the following countries:

 

Afghanistan , Albania ,Algeria ,Andorra , Angola , Antigua and Barbuda , Argentina , Armenia ,Aruba , Australia , Austria , Azerbaijan , Bahamas, The Bahrain , Bangladesh , Barbados ,Belarus , Belgium , Belize ,Benin ,Bhutan , Bolivia , Bosnia and Herzegovina , Botswana , Brazil , Brunei , Bulgaria , Burkina Faso , Burma , Burundi , Cambodia , Cameroon , Canada , Cabo Verde , Central African Republic , Chad , Chile , China, Colombia,Comoros ,Congo, Democratic Republic of the Congo, Republic of the Costa Rica , Cote d’Ivoire , Croatia , , Curacao ,Cyprus , Czechia , Denmark ,Djibouti , Dominica , Dominican Republic ,East Timor (see Timor-Leste) , Ecuador , Egypt , El Salvador , Equatorial Guinea , Eritrea , Estonia ,Ethiopia , Fiji , Finland , Gabon , Gambia, The Georgia , Germany , Ghana , Greece , Grenada , Guatemala ,Guinea , Guinea-Bissau ,Guyana,Haiti , Holy See , Honduras , Hong Kong ,Hungary ,Iceland , India , Indonesia , ,Iraq , Ireland ,Israel ,Italy , Jamaica , Japan , Jordan , Kazakhstan , Kenya , Kiribati , Korea, , South Kosovo ,Kuwait ,Kyrgyzstan , Laos , Latvia , Lebanon , Lesotho , Liberia ,Libya , Liechtenstein , Lithuania , Luxembourg , Macau , Macedonia , Madagascar, Malawi , Malaysia , Maldives , Mali , Malta , Marshall Islands ,Mauritania,Mauritius , Mexico, Micronesia , Moldova , Monaco , Mongolia , Montenegro , Morocco , Mozambique , Namibia , Nauru , Nepal, Netherlands , New Zealand , Nicaragua , Niger , Nigeria , ,Norway,Oman , Pakistan , Palau , Palestinian Territories ,Panama , Papua New Guinea ,Paraguay , Peru , Philippines , Poland , Portugal ,Qatar , Romania , Russia , Rwanda , Saint Kitts and Nevis , Saint Lucia ,Saint Vincent and the Grenadines , Samoa , San Marino , Sao Tome and Principe , Saudi Arabia , Senegal, Serbia , Seychelles , Sierra Leone, Singapore , Sint Maarten , Slovakia, Slovenia, Solomon Islands , Somalia, South Africa , South Korea,South , Spain , Sri Lanka , , Suriname , Swaziland , Sweden , Switzerland , ,Taiwan , Tajikistan , Tanzania ,Thailand , Timor-Leste, Togo , Tonga, Trinidad and Tobago ,Tunisia ,Turkey ,Turkmenistan,Tuvalu, Uganda , Ukraine , United Arab Emirates, United Kingdom , Uruguay ,Uzbekistan , Vanuatu , Venezuela ,Vietnam , Yemen , Zambia , Zimbabwe.

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Cream & Ointment Manufacturing Plant:

Application:

Pharmaceuticals: Creams, Emulsions, Gels, Ointments

Cosmetics: Lotions, Shampoo, Toothpaste

Concept: The plant facilitates the manufacturing of creams, gels, and ointments by blending basic ingredients such as glycol, water, wax, and active ingredients in precise proportions. The process involves heating the glycol and melting the wax in jacketed vessels, followed by the addition of active ingredients in the manufacturing vessel to produce the desired product.

Ointment & Cream Manufacturing Plant Batch capacities?

 

The Ointment & Cream Manufacturing Plant, Equipment, Ointment Making machine consists of a set of equipment designed for ointment, gel, cream and lotion for capacities ranging from 5 kg kilograms per batch to 10000 kg kilograms per batch…Petroleum Jelly Manufacturing Plant. Ointment Manufacturing Plant. Hair Oil Manufacturing Plant. Toothpaste Manufacturing Plant. Liquid Detergent, hand wash, Dish wash Manufacturing Plant. Gel Manufacturing Plant.